MAP3K1 and breast cancer: For example, the fibroblast growth factor receptor 2 (FGFR2), mitogen-activated kinase kinase kinase 1 (MAP3K1), lymphocyte-specific protein (LSP1), and trinucleotide repeat-containing 9 (TNRC9/LOC643714) genes, along with a 110 kb region of chromosome 8q24 have been associated with breast cancer in large studies involving thousands of subjects [60, 61].