Through fluorescently examining the level of tumor cells adhering to mesothelial cells in response to TGF-β1 treatment, we found that peritoneal fibrosis appeared to be able to promote gastric cancer cell adherence to mesothelial cells in a TGF-β1 dose-dependent manner, as compared to the control (p < 0.05). The gene discussed is TGFB1; the disease is Peritoneal Fibrosis.