SPP1 and coronary artery disorder: Multiple logistic regression analysis revealed that after adjustment for several potential confounding variables, the risk of a moderate reduction in eGFR, the presence of CAD, and a moderate reduction in eGFR or CAD increased more than fourfold (P = 0.006, P = 0.034, and P = 0.027, respectively) for OPN in the diabetic cohort (Table 4).