GRN and amyotrophic lateral sclerosis: Like TDP-43, mutations in many other genes have been found to be important in FTLD/ALS and have gained the interest from the researchers, such as those identified recently in FUS gene (MIM# 137070) (Lagier-Tourenne and Cleveland, 2009), and in the previously identified PGRN (MIM# 138945) (Gijselinck et al., 2008) and SOD1 genes (MIM# 147450) (Cleveland and Rothstein, 2001).