ACE and type 2 diabetes mellitus: Our observation with regard to the Chinese ethnic group is in contrast with the findings on Southern Chinese and other Far East Chinese populations, which demonstrated strong evidence of the deleterious effect of the D allele in the etiology of T2DM[40, 52, 53] and diabetic nephropathy.[40–42, 44] Nevertheless, our findings are in agreement with those of Wong et al.[43] who investigated the prognostic effect of an ACE I/D gene polymorphism in the diabetic nephropathy on Chinese population in Hong Kong, China.