ALB and diabetic kidney disease: Diabetic nephropathy is a syndrome characterized by albuminuria in which the urinary albumin excretion rate rises progressively over time leading to declining glomerular filtration rate (GFR) and renal fibrosis with loss of renal function, coupled with arterial hypertension, increased cardiovascular disease risk and eventually end stage renal disease (ESRD).[1, 2] This disease is marked by the initial appearance of microalbuminuria.[3] Annual ESRD incidence worldwide has been reported to escalate at an alarming rate, in particular, due to diabetic kidney disease.[4, 5]