MYH7 and familial dilated cardiomyopathy: On the other hand, sensitization to Ca2+ is likely to promote systolic function in HCM but impaires diastolic function due to an increase in cytosolic free Ca2+.[12, 13] A study on Indians by Taranjit Singh et al.[14] with a similar approach, in which MYH7 mutations were found in both HCM and DCM, further supports our data and reconfirms the fact indicating that there is a wide genetic and phenotypic heterogeneity of HCM and DCM in our population similar to that reported for other ethnic populations such as Caucasians and Japanese.[15–20]