In the present study, common genetic variations were found in MYH7 gene in both HCM and DCM samples This could be attributed to impaired energy compromise, or to dose effect of the mutant protein, or to even environmental factors/modifier gene effects responsible for an HCM to progress to a DCM phenotype in which both right and left ventricles are affected culminating into heart failure. The gene discussed is MYH7; the disease is heart failure.