MYH7 and heart failure: Mutational screening of MYH7 gene in HCM revealed five SNPs in exons 7, 12, 19 and 20 of which three were heterozygous and two were homozygous, [Figure 1, 2, 4] whereas the same SNPs were found to be homozygous [Figure 2] in DCM [Figure 3] sample, revealing the dose effect of the protein with the gross anatomical variations in the ventricles leading to heart failure in DCM cases.