Laboratory data showed marked anemia (hemoglobin 8.1 g/dL), hypoalbuminemia (2.9 g/dL), polyclonal hypergammaglobulinemia with IgG 6451 mg/dL, CRP 9.1 mg/dL, brain natriuretic peptide (BNP) 181 pg/mL, a positive antinuclear antibody at a titer of 1 : 1,280 with pure speckled pattern, and a positive anti-U1 RNP antibody (86 Index; normal range <15). Here, NPPB is linked to anemia.