MRAS and coronary artery disorder: Erdmann et al. applied less stringent statistical thresholds on their GWAS for CAD to identify any dismissed SNPs with modest effects or low allele frequencies and they found one new locus on 3q22.3 in muscle RAS oncogene homolog (MRAS) (OR = 1.15), the gene thought to play an important role in inflammation [54, 55].