SOD1 and Alzheimer disease: A two-way ANOVA for 3xTg-AD animals indicated an effect of “gender” in SOD-Mn (F(1,16) = 13.13, P < .005), GSH (F(1,16) = 90.70, P < .001), GSSG (F(1,18) = 46.80, P < .001), and GPx (F(1,18) = 23.93, P < .001) as well a “gender × exercise” interaction with respect to GSH (F(1,16) = 5.479, P < .05).