Direct associations between SSX and these proteins were not observed from coimmunoprecipitation studies, however it was found that when melanoma cell line DFW (known to express SSX) was knocked out for SSX expression, DFW cells had 40% decreased ability to migrate in soft agar compared to SSX+ DFW cells, and this reduction was accompanied by a decrease in MMP2 expression. Here, SSX2 is linked to melanoma.