Z-360, calcium bis [(R)-(-)-3-[3-{5-cyclohexyl-1-(3,3-dimethyl-2-oxo-butyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl}ureido]benzoate], is an orally active 1,5-benzodiazepine derivative cholecystokinin-2 (CCK2)/gastrin receptor antagonist that is currently under development for the treatment of pancreatic cancer [6]. The gene discussed is CCKBR; the disease is pancreatic neoplasm.