IL1B and gastric cancer: While some researchers have found that IL-1B -511TT and IL-1B -31CC are proinflammatory [32,44], others have found, with in vitro experiments and with stomach cancer patients infected with H. pylori, that the IL-1B -511C and IL-1B -31T alleles potentiate expression of IL-1β in the gastric mucosa [33,45,46].