EPHA2 confers tumorigenic and metastatic potential to non-transformed breast and skin epithelial cells, as well as mouse fibroblasts, and is overexpressed in tumor parenchyma of several cancers, including breast, bladder, prostate, colon, eosophageal, ovarian, cervical, stomach, and melanoma [4-12]. This evidence concerns the gene EPHA2 and cancer.