There were concomitant reductions in vector populations (over 90% reduced), mosquito sporozoite prevalence rates (over 90% reduced), parasite prevalence rates in children under five years of age (68% reduced), fever rates (89% reduced), and severe anaemia rates (Hb <8 gm/dl; 87% reduced) [41]. The gene discussed is GSTM1; the disease is anemia (phenotype).