To determine STAT3 expression and its phosphorylation at Y705 and S727 residues in cervical cancer, HPV positive [SiHa & CaSki (HPV16+) and HeLa (HPV18+)] and HPV- cervical cancer cell lines (C33a) were tested for expression of STAT3 and pSTAT3 (Y705 & S727) by immunoblotting. This evidence concerns the gene STAT3 and cervical cancer.