Dissemination of E. coli from the uropathogenic tract to the circulation was also undistinguishable in WT and S100A9 KO mice 24 and 48 hours after infection with 4.5×108 CFU (number of positive blood cultures; WT vs. S100A9 KO mice, t = 24: 1/7 vs. 0/8, P = 0.27 and t = 48: 0/6 vs. 1/7, P = 0.34). The gene discussed is S100A9; the disease is infection.