It is tempting to hypothesize that, despite a marked thrombocytopenia, attributed to both platelet destruction and platelet sequestration in various organs [11],[36], these P-MP:CD41+, because they are still present in the circulation, could be responsible for some of the platelet-related effects such as activation of coagulation or adhesion. The gene discussed is ITGA2B; the disease is Thrombocytopenia.