Figures 9A–C shows examples of the differential degradation in the BCP for tumor suppressors, e.g., ceruloplasmin [33], pigment epithelium-derived factor [34], and gelsolin [35], involved in angiogenesis, apoptosis, differentiation, Rac signaling, and mobility, etc. ApoA-IV, which has been reported having decreased blood concentration in cancer patients [36], is also high differentially degraded in the BCP examined (Figure 9D). The gene discussed is AKT1; the disease is neoplasm.