Chronic inflammation, characterized by the increased production of cytokines and acute-phase reactants and activation of inflammatory signalling networks [1]–[5], may be involved in the pathogenesis of type 2 diabetes (T2D).Various markers of inflammation have been shown to predict the future diabetes risk, including Interleukin-6 (IL-6) and C-reactive protein (CRP) [1], [5].Obesity, a strong risk factor for T2D is also associated with inflammation as fat tissue releases inflammatory cytokines[6], [7]. This evidence concerns the gene IL6 and obesity due to melanocortin 4 receptor deficiency.