HLA-C and neoplasm: A previous review of the literature highlighted the potential mechanisms for transfer of tumor antigen to DCs for cross-presentation [15] including; (1) phagocytosis of cell associated antigens, (2) pinocytosis/endocytosis of soluble antigen, (3) capture of soluble antigen bound to heat shock proteins (HSP), (4) gap junction transfer, (5) capture of exosomes, (6) “nibbling” of live tumor cell membranes, and (7) “cross-dressing” whereby DCs acquire peptide MHC complexes from contact with necrotic cells.