PLAT and hemorrhage: Intraventricular extension of ICH is one such mechanism [10], and there are two RCTs of ventricular drainage combined with intraventricular recombinant tissue plasminogen activator (Dutch Intraventricular Thrombolysis after Cerebral Haemorrhage Study [DITCH; ISRCTN 19105863] and Clot Lysis: Evaluation Acceleration of Resolution of IVH [CLEAR-IVH; NCT00650858]).