Because PL2L60 could promote breast cancer cell proliferation in vitro, and overexpression of PL2L60 was associated with increased nuclear NF-κB expression in tumor cell lines (Fig. 7), we further investigated whether the expression of PL2L60 or PL2L proteins was also associated with NF-κB expression in primary and metastatic cancers. This evidence concerns the gene NFKB1 and metastatic malignant neoplasm.