IFNA1 and viral infectious disease: Together with the observation that Vpx is not able to completely rescue HIV-1 from IFNα mediated inhibition, and that it has been shown to have the same enhancement of viral infection in MDDC [30] does not completely explain the total impact of IFNα on HIV-1 replication and thus it is likely that other unidentified IFNα-inducible antiviral factors exist.