The neuroprotective effects of MT3, which are presumably due to its metal-chelating and antioxidative effects, are evident in epileptic brain injury [135], cortical cryolesions [136], a mutant superoxide dismutase 1 (SOD1[G93A]) mouse model of ALS [137], and peripheral nerve injury [138]. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.