In addition, elevated apoptosis rates were found in abortion-prone mice [52] and a strong increase of Bax expression was found in the cytotrophoblast, stroma, endothelial cells and deciduas of placentas of the first trimester abortion compared to the low/moderate Bax immunopositivity in all the placental compartments during the first trimester after voluntary termination of pregnancy [53]. The gene discussed is BAX; the disease is abortion.