Interestingly, this region of CFA10 contains a good candidate gene, Sry-related Hmg-box gene 10 or Sox10. This gene is involved in Waardenburg-Shah syndrome in humans which includes deafness and hypopigmentation in its phenotype (http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602229). This evidence concerns the gene SOX10 and deafness.