Furthermore, Jeffries and colleagues [31] described a family with the chromosome translocation t(6;11)(q14.2;q25) segregating with schizophrenia-like phenotype; because the breakpoint of chromosome 11 is close to the B3GAT1 gene, it has been hypothesized [31] that polymorphic or other variations of the 11q telomere might affect the activity of B3GAT1, thus becoming a risk factor for schizophrenia and related psychoses. This evidence concerns the gene B3GAT1 and schizophrenia.