In order to target StrepGpcAdluc to murine vasculature associated with human tumour xenografts, a rat anti-mouse E-selectin IgG2a monoclonal antibody (RMES mAb) and a chimeric P-selectin Glycoprotein Ligand-1 (PSGL-1)-Fc fusion protein were tested as alternative targeting ligands. Here, SELE is linked to neoplasm.