TNF and infection: In support of this explanation, we observed similar levels of TNF in the supernatant of Cd36+/+ and Cd36-/- thioglycolate-elicited peritoneal macrophages infected with mycobacteria in vitro (Figure 7C), which increased in a dose-dependent manner with increasing multiplicity of infection with both M. marinum (Figure 7E) and BCG (Figure 7F).