In conclusion, this is the first study that confirms in children of age 2 years the previously found associations of genetic variants in the FADS1 FADS2 gene cluster with fatty acid composition in serum phospholipids or glycerophospholipids and that also analyzed the potential influence of FADS1 FADS2 genotypes and PUFAs to eczema. Here, FADS2 is linked to Eczematoid dermatitis.