The injection of different amounts of SLO in mice at the concentrations of 50 and 10 mg/kg/day, have had maximum DTH response in 48 hours; the percentage of CD8+ lymphocytes have increased in the mice injected with SLO; SLO (10 mg/kg/day) injected intraperitoneally has shown a slight non significant decrease of tumor growth rate and in addition SLO injection caused a significant increase in IFN-gamma production [43]. The gene discussed is CD8A; the disease is neoplasm.