Patients with active IBD had statistically significant higher CRP levels (median: 2.27 mg/dL, range: 0.75-31.15 mg/dL) compared to patients with inactive disease (median: 1.10 mg/dL, range: 0.00-19.20 mg/dL), (P = 0.002). This evidence concerns the gene CRP and irritable bowel syndrome.