Other chemokine-associated genes in the HRneg/Tneg signature linked to both epithelial and cancer cell expression include EXOC7 (exocyst complex component 7) [38], ABO (blood group glycosylransferases A and B) [39], CLIC5 (chloride intracellular channel 5) [40], RPS28 (40S ribosomal protein S28) [41], HAPLN1 (hyaluronan- and proteoglycan-linked protein 1) [42], and RGS4 (regulator of G-protein signaling 4) [43-46]. The gene discussed is RGS4; the disease is cancer.