In contrast to HL-60 cells that are killed via the CD95-CD95 ligand pathway [105,106], resveratrol has been reported to drive apoptosis also in CD95-signaling-resistant ALL cell lines by activating the intrinsic apoptotic pathway whereas normal peripheral blood mononuclear cells (PBMCs) are not affected [107]. The gene discussed is FAS; the disease is acute lymphoblastic leukemia.