Recent studies in non small cell lung cancer (NSCLC) have revealed that mutations in epidermal growth factor receptor (EGFR) occur in 15% of Caucasians and 30% of Asians with NSCLC, and the presence of specific EGFR mutations is predictive of response to therapy and cancer outcome [5-8]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.