ICAM1 and atherosclerosis: A single-base C to T transition polymorphism, which results in an amino acid substitution from glutamine (E) to lysine (K) in the ICAM protein in exon 6 codon 469, has been found to be related to inflammatory diseases and atherosclerosis.4 The aim of this study was to investigate the association of K469E polymorphism of the ICAM-1 gene and sICAM-1 serum level with coronary heart disease (CHD) in Egyptian subjects.