To evaluate the possibility that NG2 may be necessary for the tumor-propagating potential of PDGF-B induced gliomas, we transduced cells from two independent gliomas with the miRNA-NG2, the miRneg or a vector carrying only GFP and we injected them into the brains of adult mice (miRNA-NG2: n = 6; miRneg: n = 9 ; control GFP: n = 18). Here, PDGFB is linked to central nervous system cancer.