KIR3DL1 and HIV infectious disease: Genetic studies also provide support for a role for KIR3DS1+ and KIR3DL1+ NK cells in control of HIV replication in vivo: co-expression of HLA-Bw480I with KIR3DS1 or certain inhibitory alleles of KIR3DL1 has been found to be associated with low-level viremia in early HIV infection and also with delayed disease progression [102-104].