TLR3 and liver disorder: Recent studies have shown that TLR3 also plays important roles in the pathophysiology of a variety of liver diseases [5–7], which may attribute to the wide expression of TLR3 on all types of liver cells, including hepatocytes [8–10], stellate cells [11], sinusoidal endothelial cells [12], Kupffer cells, biliary epithelial cells [13, 14], as well as immune cells such as NK cells, NKT cells [15], and liver lymphocytes [12].