Gains of 17q23-q24 and losses of 1p39, 1p36, 1p35, 1p32, 7q21-q22, 7q34, 7q36.1-q36.3, 9p21.3, and 11q13.5 were more frequent in ER+ cases while gain of 5p15-p12 was associated with ER- cancers. The gene discussed is ESR1; the disease is cancer.