For many years, various medicinal plants have been used by people in different countries to treat or alleviate diabetes mellitus symptoms and currently studies at basic and clinical levels conducted worldwide have shown these beneficial effects.[8, 9] Mechanism of hypoglycemic effect of most of the natural antidiabetic alternatives is thought to be related to the existence of some compounds which stimulate insulin secretion from pancreatic β-cells or possess antioxidant activities.[3, 8–10]. This evidence concerns the gene INS and diabetes mellitus.