As shown in Figure 5J & 5K, although BCL2-cDNA and CKS1B-shRNA doubly-transfected cells clearly showed cell growth inhibition and death compared with SCR-transfected control cells (p <0 .05), BCL2 transfection partially abrogated myeloma cell growth inhibition and death induced by CKS1B-silencing (Figure 5J & 5K, p < 0.05). Here, CKS1B is linked to plasma cell myeloma.