Similarly, KCNE1L has been associated by Piccini et al. [32] to AMME syndrome (Alport syndrome - mental retardation - midface hypoplasia - elliptocytosis) whose symptoms include, among others, hearing loss, and analogous situations are reported also for TIMM8A, involved in Mohr-Tranebjaerg syndrome [33] and Jensen syndrome [34], and ALMS1, involved in Alström syndrome [35]. This evidence concerns the gene KCNE5 and Intellectual disability.