ATR and cerebellar ataxia: It is interesting to note that the CHD7 CRA_e translated sequence harbors six Serine/Glutamine (SQ) and two Threonine/Glutamine (TQ) motifs, which are known to be putative phosphorylation sites for the DNA damage response kinases, namely: ATM (Ataxia-Telangiectasia Mutated) and ATR (Ataxia-Telangiectasia and Rad3-related) [24].