We have evaluated three real-time ARMS assays in melanoma tumour samples: BRAF 1799T>A [this includes V600E and V600K], NRAS 182A>G [Q61R] and 181C>A [Q61K], and two real-time ARMS assays in non-small-cell lung cancer (NSCLC) samples: EGFR 2573T>G [L858R] and 2235-2249del15 [E746-A750del], for the analyses FF-PET DNA and compared the results to DNA sequencing of the exons containing mutation hot-spots for these genes (BRAF exon 15, NRAS exon 1, EGFR exons 18-21). The gene discussed is NRAS; the disease is neoplasm.