VEGFA and neoplasm: Furthermore, flavonols inhibit tumour angiogenesis and invasiveness by repressing expression of the angiogenesis-promoting vascular endothelial growth factors (Kim et al, 2006; Luo et al, 2009; Lee et al, 2010b) and invasion-promoting matrix metalloproteinases, respectively (Vijayababu et al, 2006; Lin et al, 2008; Phromnoi et al, 2009; Zhang and Zhang, 2009).