In the current study, we examined serum concentrations of eight cytokines (IL-1β, IL-2, IL-8, IL-10, IL-12p70, GMCSF, IFNγ, and TNFα) in relation to flavonol intake and colorectal adenoma recurrence and found none to be associated with flavonol intake and with colorectal adenoma recurrence. This evidence concerns the gene IL2 and colorectal adenoma.