Kaplan-Meier analysis showed that the overall tumor-free survival was significantly (P = 0.0002) longer in the bi-genic mice and that, compared to MMTV-wnt1 mice, approximately three times as many MMTV-wnt1-RARα1/KO mice were tumor-free at the end of the 40th week follow up (Figure 6C). Here, WNT1 is linked to neoplasm.