The tumor-free survival of RARα1/KO-wnt1 mice was significantly (P = 0.0002, Kaplan Meier) longer, the in vivo growth of RARα1/KO-wnt1 transplanted tumor fragments was significantly (P = 0.01) slower and RARα1/KO-wnt1 tumors cell suspension produced tumors after much longer latency. Here, WNT1 is linked to neoplasm.