EZH2 and renal cell carcinoma: For metastasized RCC, 1-5%, >5-25%, and >25-50% nuclear EZH2 expression was linked to decreased CSS when compared with tumors with undetectable EZH2 expression (HR 2.63, p = 0.043, HR 3.35, p = 0.013, HR 4.92, p = 0.003).