GCG and hydrops fetalis: Our major findings include: 1) an increase in body weight and fat mass in response to high energy diets after a weaning diet high in protein compared to fiber; 2) an increase in energy intake in rats fed a HP diet, especially when switched to a HFHS diet; 3) a decrease in glucose and increase in GLP-1 in rats fed HF; and 4) greater accumulation of triglyceride in the liver of HP-fed rats.