Interestingly, all the CpG sites related to basal-like tumors in univariate regression analysis, with the exception of RASSF1 (Table 3), belonged to this committed class A category, and in a manner analogous to hESCs; they were not hypermethylated in basal-like tumors, nor in normal breast, but they were hypermethylated in the rest of breast cancer subtypes, suggesting that basal-like tumors may share some similarities in their methylation patterns with those of the hESC cell lines. The gene discussed is RASSF1; the disease is breast cancer.